Rapid synthesis, screening, analysis and identification of engineered materials responding to, or compatible with, biological systems.
The Biointerfaces Institute is a state-of-the-art facility implementing high-throughput research workflows to investigate the nature of the biological/material interface. The institute has expertise in high-throughput synthesis and screening, surface characterization, polymer chemistry, bioassay development, ophthalmic biomaterials, development of advanced sol-gel–based biomaterials and biosensor technologies. Its members span several disciplines, including chemistry, chemical biology, biochemistry, chemical engineering and biomedical engineering.
Assay development/scale-up and formatting, point-of-care diagnostics and biosensors, biomedical materials development and screening, cataloguing and modelling of fundamental properties of biointerfaces, particle design/synthesis and characterization
- Agriculture, animal science and food
- Automotive
- Chemical industries
- Education
- Environmental technologies and related services
- Forestry and forest-based industries
- Healthcare and social services
- Information and communication technologies and media
- Life sciences, pharmaceuticals and medical equipment
- Manufacturing and processing
- Mining, minerals and metals
Specialized labs and equipment
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Specialized lab |
Equipment |
Function |
|---|---|---|
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Biological Preparation Suite
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Used for high-throughput production of bacterial and mammalian cells, proteins and DNA and for selection of DNA and RNA aptamers |
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High-Throughput Synthesis and Screening Suite
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Used for high-throughput synthesis and screening of biomaterial and biointerface libraries; can produce libraries in microwell plate, microarray and nanoparticle formats |
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Bioselectivity Suite
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Used to probe the interactions between biological entities and synthetic materials or surfaces; the information gathered provides atomic-level detail into the nature of such interactions |
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Surface Characterization Suite
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Used to examine nanoparticle properties (i.e. size, shape, charge) and properties of planar surfaces (i.e. chemical properties, polarity, charge, porosity, roughness, mechanical properties); many of the instruments can image microarrays to vastly increase throughput |
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Informatics and Database Suite
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The BioELN provides control over all aspects of the workflow, including inventory, lab notebooks, instrument booking and charges, scheduling, etc. |
Private and public sector research partners
- Pro-Lab Diagnostics
- Bruker Canada
- Physical Electronics Inc.
- Tecan
- Scienion
Additional information
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Title |
URL |
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McMaster University opens state-of-the-art biosurfaces lab |
http://www.cbc.ca/hamilton/news/story/2013/04/19/hamilton-biointerfaces.html |
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Wound-healing bandages? Germ-repelling doorknobs? McMaster opens $22 million Biointerfaces Institute |
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McMaster research facility to create medical diagnostic tools |
http://www.chch.com/mac-research-facility-to-create-medical-diagnostic-tools/ |
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Neat new materials that perform miraculously |
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How safe is your drinking water? Speaker series tackles perplexing problems |
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McMaster scientists working on new melt in your mouth vaccine |
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Mac Researchers develop healthcare game changer |
http://www.chch.com/mac-researches-develop-healthcare-game-changer/ |
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Early disease detection via inkjet printing |
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In the future, finding clean water might be as easy as snapping a photo |
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Smart phones get smart about water |
http://www.thespec.com/news-story/5629038-smartphones-get-smart-about-water/ |
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Breakthrough test can diagnose disease on the spot |
https://www.thespec.com/community-story/6250027-breakthrough-test-can-diagnose-disease-on-the-spot/ |
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Biointerfaces Institute (BI) |