Characterization of biopolymers and soft materials
The optical trapping laboratory specializes in the mechanical characterization of individual molecules and microscale materials. Expertise ranges from single-molecule measurements to microrheology. The laboratory houses state-of-the-art instrumentation, including a centrifuge force microscope and optical trapping instruments, one a dynamic holographic optical tweezers instrument useful for characterizing soft materials (such as gels and matrices) that exhibit 2- and 3-dimensional microscale heterogeneity. In characterizing the growth of materials, our expertise includes monitoring the development of viscoelastic heterogeneity at high bandwidth (>1 kHz) over time scales from seconds to hours. The comprehensive wet lab neighbouring the optical tweezers instrumentation means that we can prepare and characterize biological and chemical samples in-house.
Mechanical characterization of soft materials at the single-molecule and microscale levels.
- Agriculture, animal science and food
- Clean technology
- Life sciences, pharmaceuticals and medical equipment
- Manufacturing and processing
Specialized labs and equipment
Specialized lab | Equipment | Function |
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Optical trapping laboratory | Dynamic holographic optical tweezers | Soft materials microrheology; monitoring spatially resolved development of viscoelasticity at the microscale |
Optical tweezers | Single-molecule characterization, microrheology | |
High-throughput single-molecule manipulation laboratory | Centrifuge force microscope | Force-dependent enzymatic cleavage, ligand-receptor interactions |
Molecular biology laboratory | Cell culture facilities | |
Microscopy facilities | ||
Fast Protein Liquid Chromatography (FPLC) | ||
UV-Vis Spectrophotometer | ||
Fluorescence Plate Reader | ||
Thermocycler | ||
Gel electrophoresis and blotting | ||
Close access to many other characterization facilities |
Additional information
Title | URL |
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Video showcasing our CFI-funded infrastructure-The age-old collagen question – Nancy Forde, SFU | https://www.youtube.com/watch?v=eiZIteAWlcI |