Medicinal chemistry laboratory, Sherbrooke Pharmacology Institute

Université de Sherbrooke, Sherbrooke, Québec
What the facility does

Medicinal chemistry, drug discovery, peptide chemistry, macrocycles

Areas of expertise

The lab designs and optimizes small molecules as tools to understand (validate) the potential of new biological targets, as well as to discover new drugs. The lab has many interdisciplinary collaborations and with industry.

Research services

Medicinal chemistry, structure-activity relationships, leads identification, leads optimization, targets validation, drug discovery, macrocycles

Sectors of application
  • Chemical industries
  • Life sciences, pharmaceuticals and medical equipment

Equipment

Function

Preparative HPLC coupled to a mass spectrometer (MS-prep)

High-throughput purification of active compounds

UPLC-MS High-throughput compound analysis
Peptide synthesizer Peptide synthesis
400 MHz NMR Small molecule analysis
UPLC-MS/MS Small molecule and metabolite quantification
Parallel synthesis platform Molecule library synthesis
  • Neomed
  • Immune Biosolutions
  • Bayer Healthcare
  • Ebvia
  • ArmorChem