Sherbrooke Molecular Imaging Centre (CIMS) of the Sherbrooke University Hospital Research Centre (CRCHUS)

Université de Sherbrooke, Sherbrooke, Québec
What the facility does

Preclinical imaging platform (PET, CT, MRI, optical), radiochemistry and development of new imaging technologies

Areas of expertise

The centre provides researchers and the industry with a unique range of preclinical and clinical imaging technologies. It has recognized expertise in positron emission tomography (PET), X-ray computed tomography (CT), magnetic resonance imaging (MRI) and optical imaging. With two cyclotrons and its radiochemistry service, the centre offers a wide range of radiotracers (C-11, N-13, F-18, Cu-64, Tc-99m) and radiopharmaceuticals (FDG, FTHA, acetate, acetoacetate, carvedilol, PIB). The centre’s laboratories are also actively involved in developing new preclinical imagers and new pharmaceutical agents for preclinical and clinical imaging (radiotracers, contrast mediums and optical probes). The centre has all of the infrastructure required for in vitro and in vivo validation (in animals and in clinical environments). Its clinical work serves a large population, and it is actively involved in research on oncology, cardiology, metabolism and neurology.

Research services

Our research expertise focuses on both animals and humans:

  • Radiochemistry service that offers biomolecule labelling with different radiotracers. Measurement of the in vitro and in vivo stability of radiopharmaceuticals including biodistribution studies.
  • Preclinical and clinical imaging (PET, SPECT, CT, MRI and optical imaging).
  • Monitoring of cardiac function and metabolism by PET/CT/MRI. Cerebral imaging. Therapeutic monitoring in murine and xenograft cancer models. Imaging assessments of new drugs.
  • Pharmacokinetics analysis and image processing service using an image analysis and visualization platform.
  • Animal facilities for housing small- and medium-sized animals on location.
  • Instrumentation and engineering component that works on developing new scanners and medical devices.
Sectors of application
  • Healthcare and social services
  • Life sciences, pharmaceuticals and medical equipment

Specialized lab



Preclinical imaging

Triumph™ 8 cm PET/SPECT/CT

Functional and anatomical imaging of small animals


LabPET™ 4 cm PET

Functional imaging of small animals



Functional and anatomical imaging of small animals


Optima™ SPECT

Functional imaging of big and small animals


Varian™ 7 t MRI

Magnetic resonance imaging of small animals


QOS™ optical imager

Functional and anatomical imaging of small animals


Hidex Automatic Gamma Counter

Biodistribution analysis

Preclinical services

Animal facilities with ventilated carriers (Level II certified)

Housing on site



Digital animal files

Clinical imaging

Philips™ Gemini GXL

Functional and anatomical imaging of humans


Philips™ Gemini TF

Functional and anatomical imaging of humans


Philips™ Ingenia 3 t MRI

Magnetic resonance imaging of humans


Siemens™ 1.5 t MRI

Magnetic resonance imaging of humans



Production of radioisotopes



Production of radioisotopes


3 clean rooms

Health Canada certifications


Radiosynthesis units



Hot cells



Quality control laboratory



Analytical equipment (HPLC, UPLC, MS)



Organic chemistry laboratory



Computer cluster

Image reconstruction and processing


PET/SPECT scanner simulators

Scanner development


Instrumentation laboratory

Design of detectors, scanners and medical devices


Mechanical workshop


  • Charles River Laboratories Inc.
  • iPST
  • Medtronic
  • AngioTox (EU-FP7)
  • Université de Montréal
  • Montreal Heart Institute
  • Institut universitaire de cardiologie et de pneumologie de Québec



Research... fundamental for health | Au coeur de la vie 2014

Spotlight on Sherbrooke (3:00 to 4:23 min)

Manning Innovation Awards 2012