Medical research facility specializing in heart, lung, blood and vascular diseases, with onsite respiratory and echocardiogram clinic
The Queen’s CardioPulmonary Unit (QCPU) is a medical research facility that is focused on a bench-to-bedside philosophy with emphasis on heart, lung, blood and vascular diseases. QCPU is comprised of a state-of-the-art basic science research facility that is complemented by an onsite Kingston Health Sciences Center (KHSC) satellite clinic. Our research facility contains a flow and sorting cytometer, cell culturing suite, 2-photon confocal microscope, protein arrayer and celluSPOT, small animal tri-modality micro-scanner (CT/PET/SPECT), histology core, NGS sequencer, and Helio/Hyperion mass cytometer. QCPU’s KHSC clinic, with clinical trials research capacity, contains an echocardiography ultrasound machine, electrocardiogram machines (static and active), pulmonary stress suite and fitness equipment to create the unique ability to perform stress-ECHOS on a reclined bike. QCPU enhances existing links between clinical and basic investigators at Queen’s and fosters new collaborations between researchers in other faculties and at other universities.
- Consultation / Experimental design
- Flow and sorting cytometry
- Confocal Imaging – Fixed samples
- Confocal Imaging – Intravital
- Confocal Imaging – Live samples
- Cytometry/Molecular imaging analysis
- Cell Culturing
- Histology
- Electron Microscopy
- Hyperion Mass Cytometry
- Helios Mass Cytometry
- Mass Cytometry analysis
- Multi-analyte array
- Protein Array
- CelluSPOT
- Nucleic acid quantification
- Liquid Handling
- PCR/qPCR/RTPCR
- Next Generation Sequencing
- Bioinformatics
- Biobanking
- Small-Animal Imaging CT Scanning
- Small-Animal Imaging PET Scanning
- Small-Animal Imaging SPECT Scanning
- Radioisotope labelling
- Clinic Space
- Echocardiogram ultrasounds
- Pulmonary fitness testing
- Electrocardiograms (static and active)
- Healthcare and social services
- Life sciences, pharmaceuticals and medical equipment
- Professional and technical services (including legal services, architecture, engineering)
Specialized labs and equipment
Equipment | Function |
---|---|
SONY SH800S FACS Cell Sorter | Flow and sorting cytometer |
Leica SP8 super resolution confocal microscope | Confocal microscope capable of fixed, live or intra-vital imaging |
Illumina NextSeq 550 System | Next-generation sequencer (part of a sequencing center) |
Fluidigm CyTOF Hyperion/Helios Imaging System | Mass Cytometer |
MILabs VECTor4CT Imaging System | Small animal CT/SPECT/PET scanner |
LabLogic Scan-RAM | PET/SPECT radio TLC-Scanner |
Leica CM1860 Cryostat | Histology cryostat (part of a whole histology core) |
Leica HistoCore MULTICUT | Semi-Automated Rotary Microtome. Histology microtome (part of a whole histology core). |
Leica HistoCore PEARL | Tissue Processor. Histology processor (part of a whole histology core). |
Leica HistoCore Arcadia | Paraffin Embedding Machine. Histology embedder (part of a whole histology core). |
Intavis MultiPep RSi | Automated high-throughput peptide synthesizer |
Invatis CelluSpot Peptide Arrays | Peptide slides spotter |
Lonza 4D-Nucleofector XY Units | Automatic transfector (part of a whole cell culturing suite) |
Luminex MAGPIX System | Multi-analyte arrayer, Multi-ELISA readers |
BioSpherix Xvivo Incubation System model X3 | Hypoxia chamber (part of a whole cell culturing suite) |
Agilent xCELLigence RTCA DP | Cell Invasion and Migration equipment (part of a whole cell culturing suite) |
ThermoFisher Scientific Invitrogen Qubit 4 Fluorometer | DNA/RNA/Protein quantification and qualification |
Philips EPIQ 7G Ultrasound System | Cardiology Ultrasound machine |
GE CASE Exercise Testing System with Medisoft console | Electrocardiogram system to assess cardiac function conveniently during exercise (includes treadmill, reclined bike and upright bike) |
GE CAM HD + treadmill | Variable Electrocardiogram |
GE MAC 5500 HD | Static Electrocardiogram |
Additional information
Title | URL |
---|---|
The New Normal – Queen’s Alumni Review | https://www.queensu.ca/gazette/alumnireview/stories/new-normal |
QCPU COVID Research 2020 | https://www.youtube.com/watch?v=cJlAsFoTWLg&list=PLbVZkH5-hmmESMfre-kb6OqwyKMHmo0B0&index=1&t=15s |
Pulmonary cardiology: Circulating immune cells and the pathogenesis of pulmonary arterial hypertension | https://www.selectscience.net/editorial-articles/pulmonary-cardiology-circulating-immune-cells-and-the-pathogenesis-of-pulmonary-arterial-hypertension/?artID=50086 |