Promotes research and hands-on training in the applications of mass spectrometry to diverse problems in the chemical, biological, and clinical sciences, including metabolomics, lipidomics, and proteomics
The Centre for Biological Applications of Mass Spectrometry (CBAMS) is a high-resolution mass spectrometry facility focusing on all areas of biological mass spectrometry, with specific expertise in proteomics, lipidomics and elemental analyses in all types of biological samples. The CBAMS mandate is: 1) advancement of mass spectrometry in the chemical, biological, and clinical sciences; 2) rigorous hands-on training of personnel at the postdoctoral, PhD, MSc, diploma and BSc levels; and 3) provision of mass spectrometry support for academic research and life sciences firms in the Montreal area.
The specific services offered by CBAMS include full lipidomics analysis of cell extracts, exosomes, biofluids and tissues to measure changes in phospholipids, sphingolipids and glycerolipids. Proteomics services include shotgun protemics, top-down proteomics and PTM determinations in various sample types. The services provided by CBAMS range from experimental design through sample preparation and LC-MS analysis to data interpretation and statistical analysis. Additional CBAMS services include measurement of specific biomolecules in a variety of samples, analysis of mycotoxins and their metabolites in biological samples using comprehensive mycotoxin library and elemental analysis using ICP-MS.
- Mass measurements (for small molecules, peptides, oligonucleotides, intact proteins, lipids, etc.)
- Quantitative analysis of selected biomolecules in biofluids and tissues
- Protein characterization and identification
- Proteomics
- Metabolomics
- Lipidomics
- Elemental analysis by ICP-MS
- Metal analysis by ICP-MS
- Agriculture, animal science and food
- Chemical industries
- Clean technology
- Education
- Environmental technologies and related services
- Fisheries and aquaculture
- Forestry and forest-based industries
- Life sciences, pharmaceuticals and medical equipment
- Mining, minerals and metals
- Ocean industries
Specialized labs and equipment
| Equipment | Function |
|---|---|
| LTQ Orbitrap Velos - ETD/Thermo Scientific | Ultra-high-resolution and accurate mass for confident structural elucidation; characterization and identification of proteins from proteolytic digests of purified protein and protein complex and complex biological samples including identification of post-translational modifications; multiple fragmentation techniques deliver optimal structural characterization; metabolomics; lipidomics; drug and xenobiotic metabolism studies |
| LC-ICP-MS/Agilent 7500ce (mass analyzer: quadrupole MS) | Elemental analysis of biological samples and nanomaterials; metal analysis |